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Isle of Palms, SC 2+ Bedroom Vacation Rentals

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328 rentals found
Twin Oaks 22 by Wild Dunes, with  Amenit...

Twin Oaks 22 by Wild Dunes3 Bedroom Golf Course View Condo3 Bedrooms | 2 Bathrooms | Sleeps 8DescriptionTwin Oaks 22 at Wild Dunes Resort is a striking and inviting vacation condo, exclusively offered by Wild Dunes, located in the peaceful...

  • Isle of Palms
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
521 Carolina Blvd ~ new construction com...

521 Carolina Blvd - Lil’ Pink HouseIsle of Palms, SCOverview: Welcome to “Lil’ Pink House,” a brand-new 6-bedroom, 6.5-bathroom bespoke home finished in March 2024. This striking property offers an unparalleled blend of sophistication and...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Cozy Family Beach Home w/Private Pool & ...
3.7
(18)

Get ready for an appealing and fun-filled beach vacation when you select charming accommodation for your stay. At Carroll Realty, we are excited to tell you about this cavernous vacation home located right by the ocean. Walk a few steps to...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 13
Stay @ Path to Paradise on Isle of Palms

Path to HeavenLocation: Wild Dunes, Isle of Palms, South CarolinaOverview:Welcome to 20 Beachwood West, a impressive 4-bedroom, 3.5-bathroom vacation home located in the heart of the charming Wild Dunes community. This brand-new construction...

  • Isle of Palms
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
1408 Ocean Club by AvantStay | Oceanfron...
5.0
(3)

1408 Ocean Club invites you to savor a marvelous beach vacation in one of the biggest condominiums in Wild Dunes. 1408 Ocean Club is highlighted with gorgeous vistas of the Atlantic Ocean as well as it overlooks the completely new Ocean Club...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
Top floor 3-Bedroom Villa with Ocean Vie...

Shipwatch C421Isle of Palms, South CarolinaOverview:Welcome to Shipwatch C421, a three bedroom and three bath condo located in the Wild Dunes Resort on the Isle of Palms. This vacation home was refreshed in spring 2025 with new living room...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
NEWLY BUILT HOME, Min to Beach, Restaura...

The Eleanor House – Modern Elegance with Private Pool & Coastal CharmWelcome to The Eleanor House, a impressive new build on Isle of Palms offering the ideal blend of refined coastal design and effortless vacation comfort. Just a 5-min. walk to...

  • Isle of Palms
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
428 D Shipwatch by AvantStay | Ocean Vie...
4.9
(14)

“Mer Sea” at 428 D Shipwatch is an oceanfront penthouse condominium at Wild Dunes offering gorgeous expansive vistas of the Atlantic Ocean. What is really spectacular about 428 D Shipwatch is the range of possibilities. The two-story penthouse...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
117 Seascape by AvantStay | Oceanfront |...
3.8
(12)

You’re sure to smile as you soak in the sunrise from the oceanfront deck of this magnificent condominium in the Wild Dunes Community on the Isle of Palms! 117 Seascape is the ideal destination for your next vacation to the island! Featuring two...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
712 Ocean Blvd | New Build + Pool, Game ...

Sun, sand, and wellness collide at Stay Salty—a brand-new, oceanfront getaway on Isle of Palms where modern luxury meets intentional, healthy living. With six bedrooms (including 5 California King beds), six full bathrooms, and a powder room, this...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Oceanfront Villa in Wild Dunes Hot Tub &...

Construction Notice: This property will be undergoing major renovations during 2025. We are excited to see all of the outstanding exterior updates that will be made.​​​​​​​Plan the ultimate escape at this impressive and very roomy...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Jessamine by AvantStay | Picture Perfect...
4.6
(11)

Welcome to Jessamine! Bright, airy, and downright fun, this idyllic beach home is ideal for every occasion. Between trips to the the beach–just mins. away– your group can gather around the billiards table for some friendly competition or lay low...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Fairway Dunes 19 by Wild Dunes, with Gol...
5.0
(1)

Fairway Dunes 19 by Wild Dunes Resort3 Bedroom Resort View Condo3 Bedroom | 3 Bathroom | Sleeps 6 DescriptionEmbrace Southern appeal and resort-style relaxation at Fairway Dunes 19, a three-bedroom, three-bathroom home ideally located along the...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Stay @ After Dune Delight on Isle of Pal...
5.0
(5)

404 Summer House - After Dune DelightLocation: Isle of Palms, SCOverview:Welcome to 404 Summer House - After Dune Delight, a newly remodeled 2-bedroom, 2-bathroom vacation home located on the fourth floor, offering beautiful ocean vistas. This...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Racquet Club 22 by Wild Dunes, with Amen...

Racquet Club 22 by Wild Dunes4 Bedroom Resort View Condo4 Bedrooms | 3 Bathrooms | Sleeps 8DescriptionStep into the ultimate vacation experience at Racquet Club 22, a four-bedroom, three-bathroom vacation home offering 1,830 square feet of comfort...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
6 36th Avenue by AvantStay | Stunning Pr...

Welcome to your dream coastal getaway! Located just steps away from the sandy shores, this freshly remodeled five-bedroom, five-bathroom home is a masterpiece of luxury and comfort. The exterior is adorned with lush landscaping, creating a serene...

  • Isle of Palms
  • 5 Bedrooms
  • 6 Bathrooms
  • Sleeps 11
THE PEARL! Newly Updated 7bd/7ba IOP Hom...
4.7
(15)

Introducing THE PEARL, one of our premier properties on the Isle of Palms! This cavernous Charleston-style home was refreshed in early 2024 with wood floor throughout, updated first-floor kitchen space, upgraded bathrooms, as well as unbelievable...

  • Isle of Palms
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 20
Swim Spa, Tiki Bar, Pet friendly, Fenced...

Welcome to your vacation at the Blue House! This 4 bed, 3 bath home is freshly refreshed with all remodeled bathrooms and kitchen upgrades. Appreciate a short 2 min. walk to the beach, as this home is located just 3 homes back. A brand new Hot Tub...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8