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Isle of Palms, SC 2+ Bedroom Vacation Rentals

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328 rentals found
Coastal Manor~ 6 bdrm, across from ocean...
4.9
(16)

** During the summer we book Friday to Friday. Off-season we require a 3 nighttime minimum **--Description--'Coastal Manor' is a brand new bespoke constructed home located on Palm Blvd. right across from the ocean with a convenient beach access just...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Shipwatch C317: Oceanfront Escape in Wil...
4.7
(3)

Perched above the palm trees and looking out on the water of the Atlantic, this three bedroom, three bath Shipwatch villa offers a comfortable getaway for your Isle of Palms vacation. Savor delightful interiors, expansive vistas of the ocean and...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 7
Amazing IOP Vacation Home! 5 bedrooms wi...

NEW SWEETGRASS LISTING FOR 2025! Escape to this gorgeous 5-bedroom, 4-bathroom beach home, ideally located just two blocks from the pristine Isle of Palms beach. Designed for relaxation and entertainment, this home features a private pool and hot...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
????Coastal Sunrise????Ocean Front on Oc...
5.0
(1)

**We are Saturday to Saturday in the Summer, but we have a 3 nighttime min in the off-season**--Description--Part of our Luxury Collection, 'Coastal Sunrise', 702 Ocean Blvd. is a six bedroom, six and a half bathroom, entirely modernized (April...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 14