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4+ Bedroom Vacation Rentals

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189 rentals found
CLASSIC and Cozy IOP Beach Home, Family-...
4.7
(30)

Great Family Friendly 5 bedroom home located on a corner lot. Only two blocks from the IOP marina and close to the beach. This home is boat friendly with painless access to the IOP Boat Ramp. You will adore how this home can accommodate a very...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
????DISCOUNTS! Rare 2nd Row, Luxury Home...
4.3
(6)

**124 Charleston Blvd is Presented by Exclusive Properties Vacation Rental Agency on Isle of Palms**--Description--New to our luxury collection, 124 Charleston Blvd, 'Ocean's Genesis' is a rare gem. Be one of the first to experience this rare six...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
3108 Palm by AvantStay | Oceanfront, Pri...

★ Recognized as one of our best. This home was a finalist in the 2025 AvantStay Awards, our annual celebration of top-tier stays.Welcome to 3108 Palm, your oceanfront sanctuary on the Isle of Palms. This beach villa beckons with a private...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
1blck to Beach, Pool, Firepit, Outdoor K...
4.7
(25)

Welcome to Pelican, an AvantStay home!Just a block from the famed Island of Palms Beach, this striking, modern getaway is the ideal spot for your next coastal hideaway. An fantastic outdoor space presents a taste of heaven, where days are spent...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Palmetto by AvantStay | Gorgeous Charact...
4.7
(16)

Welcome to Palmetto, an AvantStay home!There are so many reasons you’ll appreciate it here. For starters, this lush home is just steps from the clear blue waters of Isle of Palm’s beach. But you may be tempted to spend your days swimming in the...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
ELEGANCE at the Grand Pavilion, 6 bd,Wil...

Welcome to an exceptional getaway on the Isle of Palms — a entirely reimagined, oceanfront vacation rental located at 64 Grandiose Pavilion Boulevard, in the heart of the esteemed Wild Dunes Resort. This six-bedroom, six-and-a-half-bath home is...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
Stay @ White Sands on Isle of Palms
5.0
(6)

White SandsLocation: Isle of Palms, South CarolinaOverview:Welcome to White Sands, a elegantly refreshed 4-bedroom, 4.5-bathroom coastal getaway on Palm Boulevard. Professionally designed with high-end finishes, this elegant home offers luxury...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
131 Grand Pavilion by AvantStay | Oceanf...
4.0
(3)

131 Grandiose Pavilion, located oceanfront on the Boardwalk, is certain to entice you and your family to stay here forever. Everything you will need for ideal and memorable vacation has been considered and supplied at 131 Grandiose Pavilion. The...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
New Listing! Ask about discounts! 3900 P...

New to our luxury collection, 3900 Palm Blvd. is a striking five bedroom oceanfront home. Welcome to your dream vacation home on the pristine shores of Isle of Palms, South Carolina. This grand five bedroom, four full bathrooms and two half baths...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
New pool & spa - 100 Yards from the Beac...

Escape to a spa-like getaway in the oceanside, open-concept Laurel House. Located a mere 100 yards from the beach, the airy interior invokes the spirit of the sand and sea in calming, muted shades throughout. Located on a peaceful street and...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Frank Sottile 8 Newly renovated

8 Frank Sottile | Permanent WavesLocation: Isle of Palms, SCOverview:This striking home on the Isle of Palms was completely and luxuriously modernized in 2024. Located in a calming getaway by a pond with idyllic vistas of the Harbor Course, this...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Free Charcuterie Board w/ 5 Night Stay!

Meet The Rosemary House! Located next door to her sister properties The Bella House, The Olivia House and The Grace House, this striking home features 5 bedrooms with 5 bathrooms and a private plunge pool. Where coastal meets modern, this Isle of...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Gorgeous IOP Home, Second Row, Private P...

Welcome to 4 53rd Avenue on the Isle of Palms, your ideal beach hideaway! This impressive 4-bedroom vacation rental is located on the second row from the beach, this offering simple beach access—just 50 yards away—and a partial ocean view...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
3 47th Avenue by AvantStay | Oceanfront ...

Welcome to 3 47th Avenue, where gorgeous architecture meets modern design. This cavernous getaway invites you to indulge in the ideal blend of luxury and comfort.Marvel at the unique private pool, boasting an in-water sitting area for unparalleled...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Spacious Beach Home w/Boat Parking! Easy...
3.0
(1)

Your Isle of Palms Dream Home is Waiting! Property HighlightsBoat Parking - Steps to the Isle of Palms MarinaGrand Porch - Partially Screened InGolf Course VistasTwo Living Areas - One with a Pool Table$250 Beach Gear Credit with 3-14 nighttime...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Seascapes~ 714 Ocean Blvd. Charming, Oce...

**We are Saturday to Saturday in the Summer, but we have a 3 nighttime min in the off-season**--Description--'Seascapes' 714 Ocean Blvd, is a classic oceanfront home located in the esteemed Ocean Blvd. side of the island which places the beach just...

  • Isle of Palms
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Oceanfront, Private Pool, Steps to Beach

At The Layne House, nearly every vantage offers broad vistas of the ocean while being only 5 mins. from the oceanside Wild Dunes Links and 20 mins. from the excitement downtown Charleston has to offer. Wake up to jaw-dropping, expansive ocean vistas...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Beautiful NEW LISTING IOP Waterway Blvd!...

Welcome to your dream coastal hideaway on the Isle of Palms—just 20 mins. north of historic Charleston, SC. This extravagant 4-bedroom, 4.5-bathroom beach getaway offers the ideal blend of Southern appeal and modern comfort, making it ideal for...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8