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Isle of Palms, SC 2+ Bedroom Vacation Rentals

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328 rentals found
54 Pelican Bay by AvantStay | Steps from...
4.8
(12)

54 Pelican Bay is a breath of fresh ocean air! Offering lagoon and pool vistas, 54 Pelican Bay features three bedrooms with three full baths and a half bath. 54 Pelican Bay is a second-row home and is brand new to family vacation units. A enormous...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Adorable Family Beach Home! Close to the...

29 Beachside DriveLooking for your next beach vacation? Look no further than 29 Beachside Drive. This adorable home is located within walking distance to all of the eateries and stores on Ocean Boulevard, the grocery store and more. With a community...

  • Isle of Palms
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Expansive Oceanfront Palm Blvd. 5Bd w/ P...

For those looking to experience a true oceanfront beach vacation on the Isle of Palms, this gorgeous 5 bedroom home located along beautiful Palm Boulevard is the ideal spot for your next beachfront island hideaway! This home offers charming ocean...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Walk Off OCEANFRONT Balcony to Beach! Co...
4.0
(24)

Location Location Location! This true beachfront 3 bedroom villa offers one of the best vistas in Wild Dunes. 101 Summerhouse is only steps to and from the beach and pool, making it ideal for your next vacation. With the exception of one bedroom...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
BEST Resort Location! Oceanview! Communi...
4.6
(13)

The Seagrove community of well-maintained condominiums, lush greenery, and community pool is centrally located within walking distance of the Grandiose Pavilion, Conference Center, Villages, and Wild Dunes stores and eateries. This prime location is...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
121 D Shipwatch by AvantStay | Oceanfron...
4.3
(4)

Looking for unbelievable oceanfront vistas, a sun-drenched deck that’s shaded each afternoon, cavernous floor plan and a ideal location for that calming vacation whether you’re into striking morning sunrises or handsome glistening full moons...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Sunset Point - Stunning Luxury
4.3
(4)

This oceanfront, bespoke constructed 6 bedroom/8.5 bathroom home features 7,000 square feet of pure elegance. Each room was professionally designed and no expense was spared. The attention to detail includes stone floor throughout the first floor...

  • Isle of Palms
  • 6 Bedrooms
  • 8 Bathrooms
  • Sleeps 12
Oceanview steps from the beach! 6 BR 6.5...

Stunning ocean vistas! Ready for a beach hideaway with warm sunshine, ocean breezes, sandy toes, and invigorating dips in your own private saltwater pool? Gone Coastal is a handsomely furnished 6 bedroom beach-side getaway, with only a fast 2-min...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Pavilion a la Plage on Isle of Palms ~ P...
4.8
(39)

** During the summer we book Saturday to Saturday. Off-season we require a 3 nighttime minimum **--Description--As part of our Island Collection, 'Pavilion a la Plage' 4 10th Ave, is a seven bedroom, five and a half bathroom home located in the...

  • Isle of Palms
  • 7 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
Private Pool & Spa, Luxe Interiors, with...

The Olivia House – Coastal Elegance Inside the Gates of Wild DunesTucked just behind the gates of Wild Dunes Resort and only a short walk from the sun-kissed sands of Isle of Palms, The Olivia House offers the ideal setting for your next opulent...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
203 Ocean Palms by AvantStay | Oceanfron...
4.8
(4)

You will think you found the ideal vacation when you discover "Oceanside Serenity" at 203 Ocean Palms on the Front Beach at the Isle of Palms. This is an oceanfront, four-bedroom, four-bath condominium with 2,000 square feet of living space...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
9 24th Avenue by AvantStay | Walk to Bea...
4.7
(32)

Located at #9 on 24th Avenue, this beach home features six bedrooms, six full baths, and two half baths. A beach path at the end of the block makes walking to the surf painless for the entire family, where they will find one of the best stretches of...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Conch Court 3 by Wild Dunes, Ocean View ...

Conch Court 3 by Wild Dunes4 Bedroom Ocean View Home4 Bedrooms | 4.5 Bathrooms | Sleeps 8DescriptionDiscover Coastal Charm and Modern Comfort at 3 Conch CourtEscape to 3 Conch Court—a charmingly refreshed four-bedroom, four-and-a-half-bathroom...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Oceanfront Home, Pool, Direct Beach Acce...
5.0
(1)

Make everlasting memories with you and your whole family on your next vacation at 808 Ocean Boulevard. 808 Ocean Boulevard is a elegant private 6 bedroom 6 bath home located oceanfront on the southern side of the Isle of Palms. Just mins. walk from...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 14
5 Fishers Alley by Wild Dunes

5 Fishers Alley by Wild Dunes6 Bedroom Resort View Home | Reserve6 Bedrooms | 6 Bathrooms | Sleeps 12 DescriptionFeel island luxury at its best at 5 Fishers Alley, a striking six-bedroom getaway in the exclusive Reserve collection of Wild Dunes...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
Ideal Ocean Point Location- Close to Poo...
4.4
(24)

New Kitchen, PLUS Dining and Living Room Renovations! Close and convenient proximity to Ocean Point beach and pool. Please see aerial photos 35 and 36!Inquire about our long-term winter prices on stays of 30 days or more!Located in the private...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Beautiful Oceanfront Home on Quiet Stree...
4.3
(4)

Immerse yourself in the ultimate oceanside lifestyle when you reserve this excellent 4-bedroom, 3-bathroom home that's right on the beach! Located in a private community, this amazing home features over 2,000 sq. ft..Property Highlights- Private...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Discounts!! Serenity- 2 50th~ One of a k...
5.0
(2)

Ask about our Summer 2025 discounts!! *During Summer months this home books Friday to Friday**Plug in your dates to see the full quote! Email us with any questions regarding the home or the quote. --Description--New to our Luxury Collection...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12