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6+ Bedroom Vacation Rentals

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62 rentals found
Pool, Beach Access, Walk to Town, Pet ok...

Make everlasting memories with you and your whole family on your next vacation at 808 Ocean Boulevard. 808 Ocean Boulevard is a pretty private 6 bedroom 6 bath home located oceanfront on the southern side of the Isle of Palms. Just mins. walk from...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 14
Ultimate IOP Vacation- 6BR with Pool & S...

Welcome to 2905 Palm Boulevard! Located on the charming ocean-side of the Isle of Palms, a classic beach town near historic Charleston, South Carolina, this gorgeous home was FULLY REBUILT IN 2024 and expanded to 6 roomy bedrooms - all with ensuite...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
9 24th Avenue by AvantStay | Walk to Bea...

Located at #9 on 24th Avenue, this beach home features six bedrooms, six full baths, and two half baths. A beach path at the end of the block makes walking to the surf painless for the entire family, where they will find one of the best stretches of...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Large MODERN IOP Home with Private POOL,...

Just a short drive from historic Charleston, this Isle Of Palms home on Cameron Boulevard will delight visitors looking for an ideal beach family hideaway. Featuring an broad backyard getaway with private pool and hot tub and ocean vistas from the...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Spacious Isle of Palms Beach Home with H...

Sandy CheeksLocation: 6 26th Ave Isle of Palms, SCOverview:Welcome to this entirely refreshed 6-bedroom, 3-bathroom home on the elite Isle of Palms. Ideal for families or groups, this roomy single-family home offers opulent amenities, including a...

  • Isle of Palms
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Discounts! OCEANFRONT STUNNER- Discounte...

**Ask about our current discounts for Spring/Summer 2026!Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We...

  • Isle of Palms
  • 7 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
1 Block to Beach, Newly Renovated 6BDR w...

Welcome to Sand Dune. Heaven beckons from this amazing beach home that's located only 1 block away from the sandy shores of Isle of Palms Beach. Recently remodeled in 2025, Sand Dune now features major upgrades to the kitchen and bathrooms, bringing...

  • Isle of Palms
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Family Friendly -Elegant Stay with Pool ...

The Graybrooke House – Unparalleled Vistas, Elegant Design & Private PoolWelcome to The Graybrooke House, where sweeping coastal vistas, modern luxury, and impeccable design converge. This 6-bedroom, 6 full + 2 half bath Isle of Palms getaway...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Brand New Custom Oceanfront home- Stunni...

Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in handsome, luxury or budget friendly vacation...

  • Isle of Palms
  • 6 Bedrooms
  • 8 Bathrooms
  • Sleeps 12
Spacious Coastal Home with Private Pool ...

Book June 13-20, 2026 and receive a complimentary golf cart rental for the week! BR 1: King, BR 2: King, BR 3: King BR 4: King, BR 5: King, BR 6: King, BR 7: King, BR 8: 2 Queens, BR 9: 2 Twin, BR 10: 2 Twin; Sleeps 22, Near Beach, Private Pool...

  • Isle of Palms
  • 10 Bedrooms
  • 7 Bathrooms
  • Sleeps 22
IDEAL IOP Beach Home, 6 BR, Private Pool...

This handsome 6 bedroom, 6.5 bathroom home is ready to welcome you for a once-in-a-lifetime beach escape. Just one block to the beach, it has all you need to make amazing memories on the Isle of Palms. It features two living rooms, a completely...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Coastal Manor~ 6 bdrm, across from ocean...

** During the summer we book Friday to Friday. Off-season we require a 3 nighttime minimum **--Description--'Coastal Manor' is a brand new bespoke constructed home located on Palm Blvd. right across from the ocean with a convenient beach access just...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Ultra-Luxury Oceanfront Home | 58 Grand ...

Introducing 58 Grandiose Pavilion, your unparalleled luxury escape in the heart of Wild Dunes. This enchanting oceanfront getaway, completely refreshed in 2023, offers 6 bedrooms and 6.5 bathrooms across 3,900 square feet of pure elegance.Step...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
3 47th Avenue by AvantStay | Oceanfront ...

Welcome to 3 47th Avenue, where gorgeous architecture meets modern design. This roomy getaway invites you to indulge in the ideal blend of luxury and comfort.Marvel at the unique private pool, boasting an in-water sitting area for unparalleled...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Villa Del Mare PRIVATE POOL/HOT TUB, OCE...

** During the summer we book Saturday to Saturday. Off-season we require a 3 nighttime minimum **-- Description --'Villa del Mare' is an ocean view Mediterranean masterpiece and is located just a few steps from the beach. On the calming Isle of...

  • Isle of Palms
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 20
IOP 6BD Only 3 Min Walk to Beach w/ Priv...

Welcome to #19 on 21st Avenue on the Isle of Palms! Constructed in 2019, this fantastic 6 bedroom Isle of Palms home is a 3400 square foot gem! With two enormous living areas and roomy bedrooms that comfortable sleeps 12 guests, it's ideal for huge...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
THE PEARL!  7bd/7ba IOP Home Private POO...

Introducing THE PEARL, one of our premier properties on the Isle of Palms! This roomy Charleston-style home was refreshed in early 2024 with wood floor throughout, updated first-floor kitchen space, upgraded bathrooms, as well as unbelievable...

  • Isle of Palms
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 20
IOP Home with Beach Access, Rooftop Suns...

Welcome to 118 Charleston IOP Beachhouse by AvantStay!Tucked along one of Isle of Palms’ most beloved beach corridors, this broad coastal getaway pairs easygoing Charleston appeal with effortless access to sand and surf. Just steps from a beach...

  • Isle of Palms
  • 7 Bedrooms
  • 6 Bathrooms
  • Sleeps 14