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Isle of Palms, SC 3+ Bedroom Vacation Rentals

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284 rentals found
New Ocean View Home: Pool & Putting Gree...

Overview:Welcome to 6 49th Ave - Oak and Ocean! This brand new 5 bedroom; 5 ½ bath home was just finished in January 2026 and is ready for the first lucky guests. The décor is professionally designed with a sophisticated, yet comfortable vibe. The...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Tucked in among trees, get away in this ...

Tucked away beneath mature oak trees on roughly an acre, this appealing home offers a true coastal getaway with a relaxing, private setting. Inside, you’ll find coastal-inspired décor throughout this 4-bedroom, 3-bathroom home. The main living...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Adorable Family Beach Home! Close to the...

29 Beachside DriveLooking for your next beach vacation? Look no further than 29 Beachside Drive. This adorable home is located within walking distance to all of the eateries and stores on Ocean Boulevard, the grocery store and more. With a community...

  • Isle of Palms
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Brand New Luxury 6 bedrooms, 7.5 bathroo...

Nostos~ 6 51st Ave presented by Exclusive Properties on Isle of Palms. Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
211 Seascape by AvantStay | Oceanfront V...

Discover the allure of coastal living at 211 Seascape, a three-bedroom beachfront haven located in the Seascape Condominium complex. This inviting getaway combines seamless beach access with the convenience of a community swimming pool, offering the...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 6
Gated Coastal Retreat • Ocean Views â€...

10 Ocean Point Haven is a refined Isle of Palms escape where coastal elegance, ocean vistas, and Lowcountry ease come together. Set in the gated Ocean Point community, this 4-bedroom getaway places you moments from the beach, with access to...

  • Isle of Palms
  • 4 Bedrooms
  • 5 Bathrooms
  • Sleeps 10
Sand Dune & Sea Shell by AvantStay | Gor...

**This is a two-home rental! Save additional when you book both homes at once. 12 rooms for all your family and friends!**Welcome to Sea Shell and Sand Dune by AvantStay! Heaven beckons from this marvelous beach home that's located only 1 block away...

  • Isle of Palms
  • 12 Bedrooms
  • 8 Bathrooms
  • Sleeps 24
3 47th Avenue by AvantStay | Oceanfront ...

Welcome to 3 47th Avenue, where impressive architecture meets modern design. This cavernous getaway invites you to indulge in the ideal blend of luxury and comfort.Marvel at the unique private pool, boasting an in-water sitting area for unparalleled...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Near Beach 5BR/5.5BA Isle of Palms w/ Pr...

Bright and cavernous near the beach on Isle of Palms, this welcoming 5-bedroom, 5.5-bath home is designed for painless coastal living and memorable group getaways. With room for up to 12 guests, it blends comfort, convenience, and a casual vacation...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
88 Grand Pavilion | AvantStay | Near Bea...

Savor a break from your hectic pace at 88 Grandiose Pavilion. Located on a cozy tree-lined street, this 5 bedroom, 4.5 bath home is a modern beach bungalow that is located in the heart of Wild Dunes. Finest yet, it is only a three-min. walk to the...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Cute Family Beach Home in Wild Dunes Res...

A calming and peaceful vacation experience is all yours if you visit the handsome Isle of Palms. With a long stretch of coastline, magnificant ocean, and tons of fun attractions, you can appreciate the experience to the fullest. A handsome...

  • Isle of Palms
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
AMAZING Golf and Ocean View Home! Privat...

Step inside 37 Ocean Point. A luxury five bedroom, five bathroom home in the Ocean Point neighborhood of the Wild Dunes community. Located at the very end of Wild Dunes, Ocean Point is highly sought-after due to its privacy, gorgeous and broad...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 10
Ready to make Holiday Memories? IOP 7 bd...

Your luxury vacation awaits at this remarkable Isle of Palms beach estate. Composed of seven bedrooms, seven bathrooms, countless outdoor space, and a impressive backyard getaway with pool. With elegantly-designed interiors and unending amenities...

  • Isle of Palms
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
Shared Pool + Pickleball Court + Sunroom...

Tucked just off the beach on a quieter residential stretch of Isle of Palms, Isle Be There is a bright, breezy coastal getaway made for slow mornings, salty afternoons, and casual evenings outside. Freshly refreshed and refreshed throughout, this...

  • Isle of Palms
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 7
Stay @ Bikinis & Martinis

Bikinis and MartinisLocation: Isle of Palms, SCOverview:Welcome to Bikinis and Martinis, a impressive 5-bedroom, 5.5-bathroom new construction home located just a block from the beach on Isle of Palms. This luxury getaway offers an open-concept...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Award-Winning Resort Amenities | Mariner...

Mariners Walk 9E by Wild Dunes3 Bedrooms | 3.5 Bathrooms | Sleeps 7 | Resort View________________________________________Located only mins. from the beach, this 1581 Sq. Ft. Mariners Walk unit features a complex pool and warm, family-friendly...

  • Isle of Palms
  • 3 Bedrooms
  • 4 Bathrooms
  • Sleeps 7
712 Ocean Blvd | New Build + Pool, Game ...

Sun, sand, and wellness collide at Stay Salty—a brand-new, oceanfront getaway on Isle of Palms where modern luxury meets intentional, healthy living. With six bedrooms (including 5 California King beds), six full bathrooms, and a powder room, this...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Award-Winning Resort Amenities | Twin Oa...

Twin Oaks 40 by Wild Dunes3 Bedrooms | 2 Bathrooms | Sleeps 8 | Resort View________________________________________Twin Oaks enjoys a prime setting just moments from appealing stores, gourmet eateries, and the energetic center of the resort...

  • Isle of Palms
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8