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Isle of Palms, SC 2+ Bedroom Vacation Rentals

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328 rentals found
Waterway Views, Private Pool, Hot Tub, I...

Free 4-Seater Golf Cart Rental starting January 22, 2025 for a limited time: Book now and get a complimentary golf cart rental for your 2025 vacation!Welcome to SEA'S THE DREAM! Just north of historic Charleston sits this striking 5 bedroom home...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
????Brand New???? Custom Oceanfront home...

Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in striking, luxury or budget friendly vacation...

  • Isle of Palms
  • 6 Bedrooms
  • 8 Bathrooms
  • Sleeps 12
Mariner's Walk 12C by Wild Dunes, Oceanf...

Mariners Walk 12C by Wild Dunes2 Bedroom Oceanfront Condo2 Bedrooms | 2 Bathrooms | Sleeps 4Wake up to the sight and sound of the ocean at Mariners Walk 12C, a gorgeously designed two-bedroom, two-bathroom beachfront getaway in Wild Dunes Resort...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Spacious Isle of Palms Beach Home with H...
5.0
(15)

Sandy CheeksLocation: 6 26th Ave Isle of Palms, SCOverview:Welcome to this completely refreshed 6-bedroom, 3-bathroom home on the elite Isle of Palms. Ideal for families or groups, this cavernous single-family home offers extravagant amenities...

  • Isle of Palms
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Oceanfront, Private Pool, Steps to Beach

The Layne House – Oceanfront Luxury on Isle of PalmsStep into The Layne House, an exclusive 4-bedroom, 4.5-bathroom oceanfront getaway where nearly every room captures sweeping vistas of the Atlantic. From morning coffee on the deck to sunset...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Walk to the Marina! New Wild Dunes Listi...

Escape to 38 Morgans Cove, a striking 4-bedroom, 3.5-bath vacation home in the exclusive Wild Dunes Resort on the Isle of Palms, SC—just 20 mins. from historic Charleston. This coastal getaway offers the ideal blend of relaxation, adventure, and...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Modern Beach Home in Quiet Community w/G...
5.0
(4)

Are you ready to escape to the ideal beach neighborhood in Isle of Palms? Then look no further than this delightful 3-bedroom, 2-bathroom home located right in the heart of the island! This neighborhood enjoys proximity to local stores, eateries, a...

  • Isle of Palms
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 9
121 D Shipwatch by AvantStay | Oceanfron...
4.3
(4)

Looking for unbelievable oceanfront vistas, a sun-drenched deck that’s shaded each afternoon, cavernous floor plan and a ideal location for that calming vacation whether you’re into striking morning sunrises or handsome glistening full moons...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
1 Intracoastal - Golf Views, Private Poo...
5.0
(2)

5 Bedroom, Private Pool, 12th Green on Harbor Course, Close to Isle of Palms Marina. $250 credit toward beach gear units with VayK Life (3-21 nights only). Ideal Family Getaway! Off season discounts and long-term units available until March 2025...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Oceanfront Condo in Wild Dunes! Communit...

Escape to Isle of Palms in this adorable 2-bedroom, 2-bathroom condo with sweeping vistas of the majestic Atlantic Ocean. Besides having marvelous ocean vistas and a great location, you'll also be in the Wild Dunes Resort, where you can reserve a...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
24 Fairway Dunes by AvantStay | Golf Cou...
5.0
(8)

Pretty golf vistas, outstanding décor, and a great location make 24 Fairway Dunes a place that you and your family will not want to leave. Ideally located in the Fairway Dunes Community at Wild Dunes, 24 Fairway Dunes brings together some of the...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
New Listing! Coastal Retreat, Firepit, N...

28 Sand Dollar is a modern getaway located on striking Isle of Palms, South Carolina. Tucked away on a peaceful cul-de-sac this home has every detail you could want for a calming vacation. The interior was completely modernized in 2022.Taking a look...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
'Isle be Back' 5 57th Ave- Great Ocean V...
4.8
(29)

**Summer bookings are Sat. to Sat. We have a 3 nighttime min in the off-season** Description"Isle be Back" - 5 57th Avenue is one of our newest additions. It is a elegant, six bedroom, five and a half bathroom inverted floor plan home with...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
IOP Home, Ocean and Intracoastal Views! ...

Welcome to this fun beach hideaway on the southern end of the Isle of Palms, where relaxation meets Lowcountry living. Located just a short 3-min. walk from the ocean near Breach Inlet, this three-level haven with private pool, spectacular indoor ...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
NEW CUSTOM HOME~ 620 Ocean Blvd. Now boo...

Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in pretty, luxury or budget friendly vacation...

  • Isle of Palms
  • 7 Bedrooms
  • 9 Bathrooms
  • Sleeps 12
??????? 614 Palm Blvd. Brand New ???? Cu...
5.0
(1)

**Brand New Home Completed February 2023**-614 Ocean Blvd. is Presented by Exclusive Properties Vacation Rental Agency on Isle of Palms-Ask about our Discounts!Tired of looking through tons of listings? Do you need a specific type of home or dates...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 11
Top Floor Oceanfront Penthouse  - Pool, ...

Feel your dream beachfront Carolina vacation in this three bedroom, three bathroom luxury penthouse! You'll find it located within the gated resort community of Wild Dunes on the iconic Isle of Palms. After undergoing a complete floor-to-ceiling...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Oceanfront Home, Pool, Direct Beach Acce...
5.0
(1)

Make everlasting memories with you and your whole family on your next vacation at 808 Ocean Boulevard. 808 Ocean Boulevard is a elegant private 6 bedroom 6 bath home located oceanfront on the southern side of the Isle of Palms. Just mins. walk from...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 14