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Isle of Palms, SC 2+ Bedroom Vacation Rentals

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328 rentals found
SLEEPS 10, Steps to Beach, Located withi...

The Bella House – Timeless Lowcountry Charm Steps from the BeachTucked behind the gates of the Wild Dunes Resort and just a 5-min. walk to the beach, The Bella House is a 4-bedroom, 3.5-bathroom getaway designed for effortless coastal living. With...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Fabulous IOP home! Modern NEW LISTING! P...

Escape to this impressive 5-bedroom, 4-bath beach vacation rental at 10 Wills Way on the Isle of Palms, just 20 mins. from historic Charleston. This property is new to the rental market and features all-new furnishings, offering modern comfort with...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Pavilion a la Plage on Isle of Palms ~ P...
4.8
(39)

** During the summer we book Saturday to Saturday. Off-season we require a 3 nighttime minimum **--Description--As part of our Island Collection, 'Pavilion a la Plage' 4 10th Ave, is a seven bedroom, five and a half bathroom home located in the...

  • Isle of Palms
  • 7 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
Charming updated 2 Bedroom Beach Cottage...

Family Animals are welcome! The Ideal Beach Getaway! Charming, completely refreshed, 2 Bedroom,1 bathroom Beach Cottage! Walk to the beach, grille out on the deck under the old oak tree. This beautiful home has been completely updated with a new...

  • Isle of Palms
  • 2 Bedrooms
  • 1 Bathrooms
  • Sleeps 6
PRIME Resort Location! Beachside, Ocean ...
4.7
(18)

Everything you are looking for in a beach vacation on the SC coast can be found at this impressive two-bedroom villa located in Wild Dunes Resort. The Seagrove Villas is a phenomenal community of well-maintained condos surrounded by lush greenery...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
New Listing! - 11A Mariners Walk - Ocean...

Watching the sun rise over the ocean and listening to the early morning surf: 11A Mariners Walk is really a Sunrise Retreat. Stand on the roomy oceanfront deck, as close to the beach as you can be in any home on Wild Dunes, and you will immediately...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
Oceanfront Grand Pavilion- 5 bedrooms! V...
5.0
(1)

This gorgeous, oceanfront 5 bedroom home in the Grandiose Pavilion community at Wild Dunes Resort is just what you've been searching for! The home is remodeled, you'll find new appliances, refreshed floor, and brand new furnishings throughout! But...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Southern Oasis by AvantStay | 0.5mi Walk...

Welcome to Southern Oasis, your dream hideaway on the beachy Isle of Palms! Just 30 mins. from downtown Charleston, Southern Oasis is ideal for those seeking a calming getaway located just outside of the city’s excitement.Brimming with southern...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Twin Oaks 24 by Wild Dunes, with Golf Vi...
4.5
(2)

Twin Oaks 24 by Wild Dunes3 Bedroom Golf Course View Condo3 Bedrooms | 2 Bathrooms | Sleeps 6Twin Oaks 24 at Wild Dunes Resort is a charming and roomy vacation rental located on the serene Isle of Palms, South Carolina. Located in a peaceful...

  • Isle of Palms
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
????Casa Margarita???? ~Oceanfront, 10BD...
4.8
(11)

Welcome to Casa Margarita!**904 Ocean Blvd. Presented by Exclusive Properties Vacation Rental Agency on Isle of Palms***Plug in your dates to see the full quote! Email us with any questions regarding the home or the quote or discounts. NOTE: Prices...

  • Isle of Palms
  • 10 Bedrooms
  • 11 Bathrooms
  • Sleeps 22
New Luxury Home with Oceanfront-like Vie...

**During the Summer months, bookings are Saturday to Saturday, but we have a 3 nighttime min in the off-season**Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Outdoor Oasis~Dune Ridge Lane
5.0
(2)

34 Dune Ridge Lane - Off CourseLocation: Wild Dunes | Isle of Palms, SCOverview:Welcome to “Off Course”! This charming home is located in Wild Dunes on the 9th hole of the famed Links golf course. Ideal for a beach hideaway, this property offers...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
55 Pelican Bay by AvantStay | Easy Beach...
4.8
(11)

Miles away from the real world, you'll find 55 Pelican Bay, a modernized impressive four-bedroom (2 full baths and 1 half bath) vacation home that will become your family's favorite island escape. Splash around the Pelican Bay pool, located just...

  • Isle of Palms
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Luxury Beach Rental! Private Pool & Hot ...
5.0
(1)

Welcome to 3207 Palm BlvdThis family beach home is the ideal combination of luxury and comfort with ample open spaces for either calming poolside or appreciating the ocean vistas from the rooftop deck. The architectural details and windows galore...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
Cute & Cozy 3 Bedroom Family Beach Home ...
4.8
(5)

Welcome to a peaceful, comfortable, and entirely furnished beach home for your upcoming beach vacation in Isle of Palms. Located at the center of the city, this beach home has all the necessary amenities that can ensure a convenient stay. You can...

  • Isle of Palms
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 6
3108 Palm by AvantStay | Oceanfront, Pri...

★ Recognized as one of our best. This home was a finalist in the 2025 AvantStay Awards, our annual celebration of top-tier stays.Welcome to 3108 Palm, your oceanfront sanctuary on the Isle of Palms. This beach villa beckons with a private...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Beautifully Remodeled Modern, Yet Charmi...
5.0
(12)

Your Isle of Palms Heaven Awaits!✨Property Highlights- Private Pool & Putting Green- Ocean Vistas from Second Level- Modern Beachy Decor- Steps to Public Beach Access- $250 Beach Gear Credit with 3-14 nighttime stays!Seriously, get ready to fall...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Beachfront Dream! Ideal Corner Unit, Pat...

Monthly Reservations available during Winter months! Inquire for pricing.All new reservation (3-21 nights) will receive $250 credit toward beach gear or bicycle units with VayK Life! Wake up to the gentle rhythm of ocean waves and sweeping...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4