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Isle of Palms, SC 2+ Bedroom Vacation Rentals

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328 rentals found
Luxury Beach Rental! Private Pool & Hot ...
5.0
(1)

Welcome to 3207 Palm BlvdThis family beach home is the ideal combination of luxury and comfort with ample open spaces for either calming poolside or appreciating the ocean vistas from the rooftop deck. The architectural details and windows galore...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
WILD DUNES Home with PRIVATE POOL, Golf ...
4.7
(60)

Located the exclusive Yacht Harbor area of Wild Dunes Resort on the Isle of Palms, this gorgeous 4 bedroom, 4.5 bathroom provides the ideal island hideaway. With private pool, golf course vistas, and a short walk to the IOP Marina, it's a...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Tucked in among trees, get away in this ...

Tucked away under old oak trees located on roughly an acre site, this gorgeous home is nothing short of a coastal getaway. Inside you will find coastal decor throughout this 4 bedroom 3 bath home. This home features combination kitchen/living room...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
IOP w/ Private POOL, RENOVATED, Walk to ...
4.7
(14)

Centrally located on the spectacular Isle of Palms just outside of historic Charleston, this impressive 5-bedroom home on 22nd Avenue is the ideal place to savor a family beach vacation! Having undergone a full remodel in Spring 2021, the home...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
428 D Shipwatch by AvantStay | Ocean Vie...
4.9
(14)

“Mer Sea” at 428 D Shipwatch is an oceanfront penthouse condominium at Wild Dunes offering gorgeous expansive vistas of the Atlantic Ocean. What is really spectacular about 428 D Shipwatch is the range of possibilities. The two-story penthouse...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
????DISCOUNTS! Rare 2nd Row, Luxury Home...
4.3
(6)

**124 Charleston Blvd is Presented by Exclusive Properties Vacation Rental Agency on Isle of Palms**--Description--New to our luxury collection, 124 Charleston Blvd, 'Ocean's Genesis' is a rare gem. Be one of the first to experience this rare six...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
3704 Cameron by AvantStay | Pool | Bar |...
4.9
(7)

The flavor of the Island awaits you at 3704 Cameron Boulevard. This five-bedroom, four-bath home is enchanting with its striking décor, upgraded kitchen, and an impressive private swimming pool. Plus, the beach is so close to this third-row home...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Stay @ A Wave From it All
4.5
(12)

Seascape Villas 319 - A Wave From It AllLocation: Wild Dunes, Isle of Palms, South CarolinaOverview:Welcome to A Wave From it All, a impressive 2-bedroom, 2-bathroom oceanfront villa located within the gated community of Wild Dunes. Recently...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 5
Renovated, Modern Beach Get-Away w/Priva...

3002 Cameron Boulevard Property Highlights - Pet Friendly (Weight and Breed Restrictions)- Recently Renovated - A short walk to the Beach- In ground Pool- Charmingly Landscaped Fenced Yard- Chefs Kitchen- $250 Credit towards Beach Gear (On 3 to 14...

  • Isle of Palms
  • 3 Bedrooms
  • 2 Bathrooms
  • Sleeps 8
Discounts! Beautifully decorated~ 206 Oc...
5.0
(5)

Ask about our Summer 2025 discounts! **This home books Friday to Friday in the Summer months**--Description--Part of our luxury collection, 'Villa Las Palmas', 206 Ocean Blvd., is a seven bedroom, seven and a half bathroom oceanfront home that was...

  • Isle of Palms
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
401 Yacht by AvantStay | Marina View, Co...

Why keep dreaming of the ideal island vacation, when you can experience it firsthand at 401 Yacht Harbor at Wild Dunes? This marvelous, two-bedroom, two-bath vacation destination is in one of only two condominium properties located on Morgan’s...

  • Isle of Palms
  • 2 Bedrooms
  • 2 Bathrooms
  • Sleeps 4
Stunning Wild Dunes Home-- Fire Pit, Hot...

Welcome to 10 Yacht Harbor, your dream hideaway in Wild Dunes Resort on the handsome Isle of Palms. This freshly constructed 5-bedroom vacation rental combines extravagant comfort with the casual appeal of southern coastal living. Just a short...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Gorgeous Beach Home, Ocean Views, w/Priv...

Welcome to 811 Ocean Boulevard on Isle of Palms! – An Enchanting Coastal RetreatStep into a realm of comfort and appeal as you discover this charming five-bedroom, five-bathroom home located in the heart of Isle of Palms, a heaven for both...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
521 Carolina Blvd ~ new construction com...

521 Carolina Blvd - Lil’ Pink HouseIsle of Palms, SCOverview: Welcome to “Lil’ Pink House,” a brand-new 6-bedroom, 6.5-bathroom bespoke home finished in March 2024. This impressive property offers an unparalleled blend of sophistication and...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Beautiful NEW LISTING IOP Waterway Blvd!...

Welcome to your dream coastal hideaway on the Isle of Palms—just 20 mins. north of historic Charleston, SC. This extravagant 4-bedroom, 4.5-bathroom beach getaway offers the ideal blend of Southern appeal and modern comfort, making it ideal for...

  • Isle of Palms
  • 4 Bedrooms
  • 4 Bathrooms
  • Sleeps 8
IOP Home, Ocean and Intracoastal Views! ...

Welcome to this fun beach hideaway on the southern end of the Isle of Palms, where relaxation meets Lowcountry living. Located just a short 3-min. walk from the ocean near Breach Inlet, this three-level haven with private pool, spectacular indoor ...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
405 Yacht Harbor by AvantStay | Shaded P...
4.7
(26)

Welcome to 405 Yacht Harbor! This warm and inviting marina view villa in Wild Dunes has all the appeal and comfort to make your stay on the Isle of Palms a time to remember. Featuring three bedrooms and three full baths, this incredible island...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Panoramic Marsh View,  Private w/ screen...

NEW LISTING! Tucked away on a peaceful cul-de-sac with 180 degree vistas of South Carolina's vast salt marsh landscape. This home is ideal if you're a wildlife enthusiast or just looking to get away from the bustling resort areas.Includes a...

  • Isle of Palms
  • 3 Bedrooms
  • 3 Bathrooms
  • Sleeps 8