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4+ Bedroom Vacation Rentals

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194 rentals found
IOP 6BD Only 3 Min Walk to Beach w/ Priv...

Welcome to #19 on 21st Avenue on the Isle of Palms! Constructed in 2019, this exceptional 6 bedroom Isle of Palms home is a 3400 square foot gem! With two sizable living areas and roomy bedrooms that comfortable sleeps 12 guests, it's ideal for...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Walk to the Beach + Private Pool, Roofto...

Welcome to 3602 Cameron, where beachside living meets modern elegance. Located in the heart of the Isle of Palms, this gorgeous getaway is just steps from pristine sandy shores, offering the ideal blend of relaxation and convenience. Whether you're...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Whispering Palms- The Perfect Beach Hous...

-- Description --As part of our Island Collection, 8 31st Ave is a striking beach home you won't forget. Located just one short block from the ocean, you can comfortably hop on the beach path at the end of the street. Savor spending beach time with...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Discounts! OCEANFRONT STUNNER- Discounte...

**Ask about our current discounts for Spring/Summer 2026!Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We...

  • Isle of Palms
  • 7 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Private Pool + Outdoor Lounge + Movie Ro...

Welcome to Summerset, a bright and attractively designed coastal getaway where sunlight, space, and effortless indoor-outdoor living take center stage. Located on Isle of Palms, this home places you just moments from wide sandy beaches, swaying...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
IOP Designer Home w/ Pool, Hot Tub & Wal...

The Olivia House – Coastal Elegance Inside the Gates of Wild DunesTucked just behind the gates of Wild Dunes Resort and only a short walk from the sun-kissed sands of Isle of Palms, The Olivia House offers the ideal setting for your next opulent...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
'Isle be Back' 5 57th Ave- Great Ocean V...

**Summer bookings are Sat. to Sat. We have a 3 nighttime min in the off-season** Description"Isle be Back" - 5 57th Avenue is one of our newest additions. It is a delightful, six bedroom, five and a half bathroom inverted floor plan home with...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
3 47th Avenue by AvantStay | Oceanfront ...

Welcome to 3 47th Avenue, where striking architecture meets modern design. This cavernous getaway invites you to indulge in the ideal blend of luxury and comfort.Marvel at the unique private pool, boasting an in-water sitting area for unparalleled...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Oceanview steps from the beach! 6 BR 6.5...

Spectacular ocean vistas! Ready for a beach hideaway with warm sunshine, ocean breezes, sandy toes, and invigorating dips in your own private saltwater pool? Gone Coastal is a handsomely furnished 6 bedroom beach-side getaway, with only a fast...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Beautiful home with a gorgeous saltwater...

Only 1 block from the beach! Telephone for short stays! This handsome 5 bedroom home was newly refreshed. The home sits on a enormous lot and has a beautiful saltwater pool, marvelous screened-in back porch and spectacular front porch. The roomy...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
521 Carolina Blvd ~ new construction com...

521 Carolina Blvd - Lil’ Pink HouseIsle of Palms, SCOverview: Welcome to “Lil’ Pink House,” a brand-new 6-bedroom, 6.5-bathroom bespoke home finished in March 2024. This striking property offers an unparalleled blend of sophistication and...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
3704 Cameron by AvantStay | Pool | Bar |...

The flavor of the Island awaits you at 3704 Cameron Boulevard. This five-bedroom, four-bath home is enchanting with its gorgeous décor, upgraded kitchen, and an amazing private swimming pool. Plus, the beach is so close to this third-row home, your...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Private Oasis with large pool, 4 bedroom...

Private getaway with huge private pool! Located at 103 Forest Trail, tucked away from all the traffic, this home is only a short drive to the beach or the boat marina for water sports, fishing charters, eco tours, and more! This bright and open...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
IOP w/ Private POOL, RENOVATED, Walk to ...

Centrally located on the spectacular Isle of Palms just outside of historic Charleston, this gorgeous 5-bedroom home on 22nd Avenue is the ideal place to savor a family beach vacation! Renovated in 2021, this home provides a modern, upgraded twist...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Hot tub, Private Pool, Pet Friendly, Sun...

Brand New Hot Tub just added! Appreciate the vistas of Hamlin Creek, the Intracoastal Waterway, and the impressive sunsets seen from the second story wrap around deck of Palmetto Sunset. It is a five-bedroom, three-bathroom home directly across...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Southern Oasis by AvantStay | 0.5mi Walk...

Welcome to Southern Oasis, your dream hideaway on the beachy Isle of Palms! Just 30 mins. from downtown Charleston, Southern Oasis is ideal for those seeking a calming getaway located just outside of the city’s excitement.Brimming with southern...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
THE PEARL!  7bd/7ba IOP Home Private POO...

Introducing THE PEARL, one of our premier properties on the Isle of Palms! This roomy Charleston-style home was refreshed in early 2024 with wood floor throughout, updated first-floor kitchen space, upgraded bathrooms, as well as unbelievable...

  • Isle of Palms
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 20
4 36th Avenue by AvantStay |???? ????? C...

If you’re looking for a sophisticated yet appealing beach home as a getaway from the ebbs and flows of life, 4 on 36th Avenue is where you want to be. Featuring ocean vistas from both the rooftop deck, and the pool deck, this newly constructed...

  • Isle of Palms
  • 5 Bedrooms
  • 6 Bathrooms
  • Sleeps 12