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Isle of Palms, SC 5+ Bedroom Vacation Rentals

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121 rentals found
Hot tub, Private Pool, Pet Friendly, Sun...
4.2
(5)

Brand New Hot Tub just added! Savor the vistas of Hamlin Creek, the Intracoastal Waterway, and the handsome sunsets seen from the second story wrap around deck of Palmetto Sunset. It is a five-bedroom, three-bathroom home directly across from the...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
712 Ocean Blvd | New Build + Pool, Game ...

Sun, sand, and wellness collide at Stay Salty—a brand-new, oceanfront getaway on Isle of Palms where modern luxury meets intentional, healthy living. With six bedrooms (including 5 California King beds), six full bathrooms, and a powder room, this...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Seascapes~ 714 Ocean Blvd. Charming, Oce...

**We are Saturday to Saturday in the Summer, but we have a 3 nighttime min in the off-season**--Description--'Seascapes' 714 Ocean Blvd, is a classic oceanfront home located in the esteemed Ocean Blvd. side of the island which places the beach just...

  • Isle of Palms
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
913 Carolina Boulevard by AvantStay | Pr...
4.4
(19)

Come drop your anchor on the Isle of Palms for your next family vacation at 913 Carolina Boulevard! This seven-bedroom home is the ideal place to relax and relax with incredible amenities, simple beach access, and a private swimming pool constructed...

  • Isle of Palms
  • 7 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
????Brand New???? Custom Oceanfront home...

Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in impressive, luxury or budget friendly vacation...

  • Isle of Palms
  • 6 Bedrooms
  • 8 Bathrooms
  • Sleeps 12
Gorgeous Beach Home, Ocean Views, w/Priv...

Welcome to 811 Ocean Boulevard on Isle of Palms! – An Enchanting Coastal RetreatStep into a realm of comfort and appeal as you discover this elegant five-bedroom, five-bathroom home located in the heart of Isle of Palms, a heaven for both...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Private Pool, Elevator, Golf Cart (fee),...

Incredible 5 Bedroom, 4.5 bath home with new elevated Salt Water Pool, fresh furnishings and coastal décor. Executive Kitchen with Sub Zero, Wolf and Bosch appliances entirely equipped for the cooks on vacation. The dining Room seats 8 with room...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Classic Family Beach Home w/Game Room & ...
4.8
(6)

Looking for your next family vacation rental? Take a look at this magnificent 5-bedroom, 3-bathroom home that's just a 3 min. walk to the beach! With plenty to appreciate both inside and outside, this property has all the features you could want for...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Discounts! Beautifully decorated~ 206 Oc...
5.0
(5)

Ask about our Summer 2025 discounts! **This home books Friday to Friday in the Summer months**--Description--Part of our luxury collection, 'Villa Las Palmas', 206 Ocean Blvd., is a seven bedroom, seven and a half bathroom oceanfront home that was...

  • Isle of Palms
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Spacious Beach Home w/Boat Parking! Easy...
3.0
(1)

Your Isle of Palms Dream Home is Waiting! Property HighlightsBoat Parking - Steps to the Isle of Palms MarinaEnormous Porch - Partially Screened InGolf Course VistasTwo Living Areas - One with a Pool Table$250 Beach Gear Credit with 3-14 nighttime...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Large MODERN IOP Home with Private POOL,...

Located on the Isle of Palms, just a short drive from historic Charleston, this grandiose six bedroom, five and half bathroom home on Cameron Boulevard will delight visitors looking for an ideal beach family hideaway. Featuring an broad backyard...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
????Casa Flamingo????Oceanfront Dreamhou...
4.9
(14)

Welcome to Casa Flamingo! Presented by Exclusive Properties on Isle of Palms. *Plug in your dates to see the full quote! Email us with any questions regarding the home or the quote or discounts. **Available all year! During the Summer months...

  • Isle of Palms
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 18
ELEGANCE at the Grand Pavilion, 6 bd,Wil...

Welcome to an exceptional getaway on the Isle of Palms — a completely reimagined, oceanfront vacation rental located at 64 Grandiose Pavilion Boulevard, in the heart of the esteemed Wild Dunes Resort. This six-bedroom, six-and-a-half-bath home is...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
Spacious Beach Home w/Private Pool, Elev...
4.6
(16)

3105 Palm Blvd Welcome to 3105 Palm Blvd, an striking 5-bedroom, 5-bathroom home with an elevator! When you stay at this home you'll savor bathrooms with tiled floor, gorgeously tiled walk-in showers, and modern vanities and lighting. Add in the...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Oceanfront Grand Pavilion- 5 bedrooms! V...
5.0
(1)

This striking, oceanfront 5 bedroom home in the Grandiose Pavilion community at Wild Dunes Resort is just what you've been searching for! The home is modernized, you'll find new appliances, refreshed floor, and brand new furnishings throughout! But...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Beautiful home with a gorgeous saltwater...
4.9
(7)

Only 1 block from the beach! Telephone for short stays! This striking 5 bedroom home was newly refreshed. The home sits on a huge lot and has a alluring saltwater pool, magnificent screened-in back porch and spectacular front porch. The cavernous...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Spacious Isle of Palms Beach Home with H...
5.0
(15)

Sandy CheeksLocation: 6 26th Ave Isle of Palms, SCOverview:Welcome to this completely refreshed 6-bedroom, 3-bathroom home on the elite Isle of Palms. Ideal for families or groups, this roomy single-family home offers opulent amenities, including a...

  • Isle of Palms
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
Beachwood East 19 by Wild Dunes, Ocean V...
4.5
(8)

Beachwood East 19 by Wild Dunes7 Bedroom Oceanfront Home7 Bedrooms | 7 Bathrooms | Sleeps 16 | OceanfrontDescriptionPlease note: Boardwalk beach access from the back deck is temporarily closed for beach renourishment. However, guests can still...

  • Isle of Palms
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 16