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Isle of Palms, SC 5+ Bedroom Vacation Rentals

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112 rentals found
Lux. IOP Beach 7 Bed Home, Christmas Wee...

Imagine watching the big game from your pool or hot tub... Your luxury vacation awaits at this remarkable Isle of Palms beach estate. Composed of seven bedrooms, seven bathrooms, countless outdoor space, and a gorgeous backyard getaway with pool...

  • Isle of Palms
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 16
'Villa Del Mare' ~ PRIVATE POOL/HOT TUB,...

** During the summer we book Saturday to Saturday. Off-season we require a 3 nighttime minimum **-- Description --'Villa del Mare' is an ocean view Mediterranean masterpiece and is located just a few steps from the beach. On the calming Isle of...

  • Isle of Palms
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 20
IDEAL IOP Beach Home, 6 BR, Private Pool...

This beautiful 6 bedroom, 6.5 bathroom home is ready to welcome you for a once-in-a-lifetime beach escape. Just one block to the beach, it has all you need to make marvelous memories on the Isle of Palms. It features two living rooms, a entirely...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Beautiful home with a gorgeous saltwater...

Only 1 block from the beach! Telephone for short stays! This charming 5 bedroom home was newly refreshed. The home sits on a huge lot and has a pretty saltwater pool, incredible screened-in back porch and spectacular front porch. The roomy updated...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
1blck to Beach, Pool, Firepit, Outdoor K...

Welcome to Pelican, an AvantStay home!Just a block from the famed Island of Palms Beach, this beautiful, modern getaway is the ideal spot for your next coastal hideaway. An amazing outdoor space presents a taste of heaven, where days are spent...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
2910 Palm Blvd- New Oceanfront Luxury- P...

**Ask about our current discounts!! Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in beautiful...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
Summer Rates Lowered!! Ultimate IOP Vaca...

Welcome to 2905 Palm Boulevard! Located on the beautiful ocean-side of the Isle of Palms, a classic beach town near historic Charleston, South Carolina, this gorgeous home was FULLY REBUILT IN 2024 and expanded to 6 roomy bedrooms - all with...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
Spacious Isle of Palms Beach Home with H...

Sandy CheeksLocation: 6 26th Ave Isle of Palms, SCOverview:Welcome to this completely refreshed 6-bedroom, 3-bathroom home on the elite Isle of Palms. Ideal for families or groups, this roomy single-family home offers opulent amenities, including a...

  • Isle of Palms
  • 6 Bedrooms
  • 4 Bathrooms
  • Sleeps 14
2 Condos in Wild Dunes, Pool + Hot Tub, ...

Welcome to 401 Yacht & 405 Yacht by AvantStay! These two condos are located in the Yacht Harbor Condominiums with a combined total of 5 bedrooms, sleeping 12 guests—an ideal option for family trips or groups looking to spread out.Yacht Harbor...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Golf Views, Private Pool, Screen Porch, ...

5 Bedroom, Private Pool, 12th Green on Harbor Course, Close to Isle of Palms Marina. $250 credit toward beach gear units with VayK Life (3-21 nights only). Ideal Family Getaway! Off season discounts and long-term units available until March 2025...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
'Isle be Back' 5 57th Ave- Great Ocean V...

**Summer bookings are Sat. to Sat. We have a 3 nighttime min in the off-season** Description"Isle be Back" - 5 57th Avenue is one of our newest additions. It is a elegant, six bedroom, five and a half bathroom inverted floor plan home with...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
Fabulous IOP home! Modern NEW LISTING! P...

Escape to this impressive 5-bedroom, 4-bath beach vacation rental at 10 Wills Way on the Isle of Palms, just 20 mins. from historic Charleston. This property is new to the rental market and features all-new furnishings, offering modern comfort with...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
????Casa Flamingo????Oceanfront Dreamhou...

Welcome to Casa Flamingo! Presented by Exclusive Properties on Isle of Palms. *Plug in your dates to see the full quote! Email us with any questions regarding the home or the quote or discounts. **Available all year! During the Summer months...

  • Isle of Palms
  • 8 Bedrooms
  • 6 Bathrooms
  • Sleeps 18
5 32nd Avenue by AvantStay | Gourmet Kit...

5 32nd Avenue, is the ideal heading to lead you to the ideal beach vacation on the Isle of Palms at 5 on 32nd Avenue. This handsome home is modeled in a nautical theme, straight from a 1920’s racing sailing schooner. Heart of Pine floors, white...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
New Listing! Lagoon View, close to Beach...

Brand new to the rental program! Remodeled in 2024 with all rooms freshly painted, refinished wood floors throughout, and a new kitchen. Incredible 5 Bedroom vacation home in the exclusive gated Ocean Point Community of Wild Dunes Resort. Access to...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
3 47th Avenue by AvantStay | Oceanfront ...

Welcome to 3 47th Avenue, where gorgeous architecture meets modern design. This cavernous getaway invites you to indulge in the ideal blend of luxury and comfort.Marvel at the unique private pool, boasting an in-water sitting area for unparalleled...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Summer Dunes Lane 1 by Wild Dunes, Ocean...

Summer Dunes Lane 1 by Wild Dunes7 Bedrooms | 6 Bathrooms | Sleeps 27 | Ocean View ________________________________________Welcome to Summer Dunes Lane 1, a gorgeous getaway on Isle of Palms’ exclusive Wild Dunes Resort. This classic...

  • Isle of Palms
  • 7 Bedrooms
  • 6 Bathrooms
  • Sleeps 16
????Brand New Luxury~ 6 bedrooms, 7.5 ba...

Nostos~ 6 51st Ave presented by Exclusive Properties on Isle of Palms. Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12