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5+ Bedroom Vacation Rentals

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130 rentals found
One Block to Beach! Modern 6 Bed with Pr...

Wake up to the sound of the ocean and savor your morning coffee on one of two huge covered decks, just a 5-min. walk from the beach. Spend your days calming on the sand, exploring the marina, or unwinding by the private saltwater pool in the...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
302 Charleston by AvantStay | Stunning P...

Welcome to your idyllic hideaway at 302 Charleston Blvd on the enchanting Isle of Palms, SC! This charming vacation rental home offers five bedrooms and three and a half baths, ensuring ample space for relaxation and recreation. A highlight of this...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Premier, Modern Home with Pool! Great IO...

Welcome to Three Oaks!This Isle of Palms beach home is one of our most opulent rental properties and is the ideal spot for your next vacation! Located less than 5 mins. walking to the beach via access paths at either 23rd or 25th Avenue, it...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Discounts!! Serenity- 2 50th One of a ki...

*During Summer months this home books Friday to Friday**Plug in your dates to see the full quote! Email us with any questions regarding the home or the quote. --Description--New to our Luxury Collection, 'Serenity- 2 50th Ave." is a freshly...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
Stunning Brand NEW Build, 6 bd OCEANVIEW...

Welcome to your BRAND NEW Isle of Palms beach getaway, where thoughtful design, elevated amenities, and effortless coastal living come together just steps from the beach. Located on a peaceful street and ideal for sizable groups, this striking new...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
Oceanfront 5BR home with private pool, h...

**Shuga Shack- 2614 Palm Blvd. is presented by Exclusive Properties Vacation Rental Agency on Isle of Palms** --Description--This gorgeous oceanfront home offers striking ocean vistas, direct beach access, a private pool, putting green, fire pit...

  • Isle of Palms
  • 5 Bedrooms
  • 6 Bathrooms
  • Sleeps 10
Expansive Oceanfront Palm Blvd. 5Bd w/ P...

For those looking to experience a true oceanfront beach vacation on the Isle of Palms, this gorgeous 5 bedroom home located along charming Palm Boulevard is the ideal spot for your next beachfront island hideaway! This home offers striking ocean...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Casa Margarita - Luxury Oceanfront, Priv...

Casa Margarita | Oceanfront Luxury for the Ultimate Isle of Palms GetawayWelcome to Casa Margarita, an extraordinary oceanfront getaway located at 904 Ocean Boulevard. Designed for memorable family get-togethers, group vacations, and special...

  • Isle of Palms
  • 10 Bedrooms
  • 11 Bathrooms
  • Sleeps 22
IOP Home with Beach Access, Rooftop Suns...

Welcome to 118 Charleston IOP Beachhouse by AvantStay!Tucked along one of Isle of Palms’ most beloved beach corridors, this broad coastal getaway pairs easygoing Charleston appeal with effortless access to sand and surf. Just steps from a beach...

  • Isle of Palms
  • 7 Bedrooms
  • 6 Bathrooms
  • Sleeps 14
IOP 6BD Only 3 Min Walk to Beach w/ Priv...

Welcome to #19 on 21st Avenue on the Isle of Palms! Constructed in 2019, this amazing 6 bedroom Isle of Palms home is a 3400 square foot gem! With two huge living areas and roomy bedrooms that comfortable sleeps 12 guests, it's ideal for enormous...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
5 32nd Avenue by AvantStay | Gourmet Kit...

5 32nd Avenue, is the ideal heading to lead you to the ideal beach vacation on the Isle of Palms at 5 on 32nd Avenue. This impressive home is modeled in a nautical theme, straight from a 1920’s racing sailing schooner. Heart of Pine floors, white...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
7 Beachwood East by AvantStay | Ocean Vi...

Step into the epitome of luxury and relaxation at 7 Beachwood East, a freshly constructed modern beach home located in a gated community just one lot back from the ocean. Ideal for family get-togethers or group getaways, this 7-bedroom masterpiece...

  • Isle of Palms
  • 7 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
Lagoon View, Walk to Beach: 5-7 min, Res...

Remodeled in 2024 with all rooms freshly painted, refinished wood floors throughout, and a new kitchen. Incredible 5 Bedroom vacation home in the exclusive gated Ocean Point Community of Wild Dunes Resort. Access to the Ocean Point community pool...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 10
Escape to Global Elegance: A Coastal San...

Escape to Global Elegance: A Coastal Sanctuary at #6 - 31st Avenue!Property Highlights:--Unmatched modern luxury--Generous Private Pool --A few mins. walk to the beach--Chef's Kitchen--Elevator--$250 Beach Gear Credit with 3-14 nighttime...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
Paradise awaits! 7 Bedroom, Private Neig...

Isle of Palms Getaway – Pool, Beach, Dining & Fun Right Outside Your Door!Everything you need for the ideal beach vacation is right at your fingertips! This handsome Isle of Palms home sleeps up to 14 guests, with 7 cavernous bedrooms and 5 full...

  • Isle of Palms
  • 7 Bedrooms
  • 5 Bathrooms
  • Sleeps 14
Brand New Luxury 6 bedrooms, 7.5 bathroo...

Nostos~ 6 51st Ave presented by Exclusive Properties on Isle of Palms. Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 12
1 block to beach! 500 Carolina Blvd. 5 b...

Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in handsome, luxury or budget friendly vacation...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
IDEAL IOP Beach Home, 6 BR, Private Pool...

This pretty 6 bedroom, 6.5 bathroom home is ready to welcome you for a once-in-a-lifetime beach escape. Just one block to the beach, it has all you need to make magnificent memories on the Isle of Palms. It features two living rooms, a completely...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12