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Isle of Palms, SC 4+ Bedroom Pet-Friendly Vacation Rentals

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41 rentals found
Charming Classic Beach Home w/Private Po...

This handsome 4-bedroom, 3-bathroom property has a great location across from the Intracoastal Waterway, with peek-a-boo water vistas and just a short walk from the beach. With a private pool and outdoor beach shower, this home is ideal for those...

  • Isle of Palms
  • 4 Bedrooms
  • 2 Bathrooms
  • Sleeps 10
Stunning Brand NEW Build, 6 bd OCEANVIEW...

Welcome to your BRAND NEW Isle of Palms beach getaway, where thoughtful design, elevated amenities, and effortless coastal living come together just steps from the beach.Located on a peaceful street and ideal for huge groups, this gorgeous new...

  • Isle of Palms
  • 6 Bedrooms
  • 7 Bathrooms
  • Sleeps 14
Summer Sale! Walk to Beach, Private Pool...

Welcome to Southern Oasis, your dream hideaway on the beachy Isle of Palms! Just 30 mins. from downtown Charleston, Southern Oasis is ideal for those seeking a calming getaway located just outside of the city’s excitement.Brimming with southern...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
Oceanfront! Pool, Hot Tub, Walk to Town,...

$250 gift card for WEEK stays!Qualifying weeks are - May 30-June 6, June 13-20th, Aug 1 - 8thWelcome to 910 Ocean Boulevard! This oceanfront getaway has something for the entire family. Choose your favorite spot from multiple oceanfront decks...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
NEW CUSTOM HOME 620 Ocean Blvd. Now book...

Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We specialize in handsome, luxury or budget friendly vacation...

  • Isle of Palms
  • 7 Bedrooms
  • 9 Bathrooms
  • Sleeps 12
Screen porch, Golf Cart, Pet friendly, L...

All new reservation (3-21 nights) will receive $250 credit toward beach gear units with VayK Life!Charming Island home with hot tub! Unwind in the living room with flat-screen TV, den, and 2 front verandas, all with ample seating. Entirely outfitted...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
'Isle be Back' 5 57th Ave- Great Ocean V...

**Summer bookings are Sat. to Sat. We have a 3 nighttime min in the off-season** Description"Isle be Back" - 5 57th Avenue is one of our newest additions. It is a pretty, six bedroom, five and a half bathroom inverted floor plan home with...

  • Isle of Palms
  • 6 Bedrooms
  • 5 Bathrooms
  • Sleeps 16
Hot tub, Private Pool, Pet Friendly, Sun...

Brand New Hot Tub just added! Savor the vistas of Hamlin Creek, the Intracoastal Waterway, and the impressive sunsets seen from the second story wrap around deck of Palmetto Sunset. It is a five-bedroom, three-bathroom home directly across from the...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 12
Gorgeous Beach Home, Ocean Views, w/Priv...

Welcome to 811 Ocean Boulevard on Isle of Palms! – An Enchanting Coastal RetreatStep into a realm of comfort and appeal as you discover this enchanting five-bedroom, five-bathroom home located in the heart of Isle of Palms, a heaven for both...

  • Isle of Palms
  • 5 Bedrooms
  • 5 Bathrooms
  • Sleeps 12
????'Dolphin Manor' ~ OCEAN FRONT, PRIVA...

** During the summer and holidays we book Saturday to Saturday. Off-season we require a 3 nighttime minimum **Description'Dolphin Manor' -512 Ocean Blvd, was completely modernized and is the ideal oceanfront home for your hideaway! With light filled...

  • Isle of Palms
  • 6 Bedrooms
  • 6 Bathrooms
  • Sleeps 12
7BR Coastal Retreat • Walk to Beach + ...

Just steps from Isle of Palms’ Front Beach scene, 6 10th Avenue puts big-group coastal living right where guests want to be—near the sand, surf, eateries, ice cream stores, and live music that make this Charleston-area beach town so painless to...

  • Isle of Palms
  • 7 Bedrooms
  • 5 Bathrooms
  • Sleeps 15
Historic Home near the Beach w/ Pool | 3...

Welcome to 306 Charleston Roosevelt Retreat by AvantStay, a rare Isle of Palms gem where coastal ease meets rich American history. Constructed in 1958 by Nicholas G. Roosevelt—a cousin of Franklin D. Roosevelt and a direct descendant of the...

  • Isle of Palms
  • 5 Bedrooms
  • 4 Bathrooms
  • Sleeps 12
29 24th Avenue by AvantStay | Easy Beach...

Gather your family together and treat them to a dream vacation at 29 on 24th Avenue on the Isle of Palms. This four-bedroom, three bath home has the amenities that will make everybody’s dreams come true. The kids will run straight to the new pool...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Pet-Friendly Wild Dunes Stay – Pool Ac...

The Carolina House – Roomy, Pet-Friendly Coastal Comfort in Wild DunesWelcome to The Carolina House, a classic Lowcountry getaway tucked within a private, gated enclave inside the acclaimed Wild Dunes Resort on Isle of Palms. This 4-bedroom...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Walk to the Marina! Wild Dunes 4BD Listi...

Escape to 38 Morgans Cove, a impressive 4-bedroom, 3.5-bath vacation home in the exclusive Wild Dunes Resort on the Isle of Palms, SC - just 20 mins. from historic Charleston. This coastal getaway offers the ideal blend of relaxation, adventure, and...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Swim Spa, Tiki Bar, Pet friendly, Fenced...

Welcome to your vacation at the Blue House! This 4 bed, 3 bath home is freshly refreshed with all remodeled bathrooms and kitchen upgrades. Savor a short 2 min. walk to the beach, as this home is located just 3 homes back. A brand new Hot Tub has...

  • Isle of Palms
  • 4 Bedrooms
  • 3 Bathrooms
  • Sleeps 8
Spacious, Family Beach Home! Ping Pong, ...

Welcome to #32 - 41st Ave! This roomy, refreshed five-bedroom beach home has a modern look, comfortable feel, and is ideal for your family to appreciate a beach vacation! Property Highlights- 3 Living Areas - All with Intelligent TVs- Free High...

  • Isle of Palms
  • 5 Bedrooms
  • 3 Bathrooms
  • Sleeps 10
Discounts! OCEANFRONT STUNNER- Discounte...

**Ask about our current discounts for Spring/Summer 2026!Tired of looking through tons of listings? Do you need a specific type of home or dates? We are a local family owned company, Exclusive Properties, located right here on Isle of Palms. We...

  • Isle of Palms
  • 7 Bedrooms
  • 6 Bathrooms
  • Sleeps 12